After a Soviet space station crashes into a New York City subway tunnel, a species of venomous spiders is discovered, and soon they mutate to gigantic proportions and wreak havoc on the city.

A quest that begins as a personal vendetta for the fierce Cimmerian warrior soon turns into an epic battle against hulking rivals, horrific monsters, and impossible odds, as Conan realizes he is the only hope of saving the great nations of Hyboria from an encroaching reign of supernatural evil.