Two friends grow up together in the Sicily of the '50s. Two different destiny, two different way of life. Could their friendship survive to the mafia shadow?

A Mafia boss is enraged when he is suspected of smuggling a heroin shipment into San Francisco. He dispatches his nephew, a hotshot Anglo-Sicilian lawyer, to identify the real culprit. The lawyer also enlists the aid of his best friend, a grand prix driver with an adventurous streak.

Joe Dallesandro plays a hungry young buck who aspires to be a career criminal. He starts out working at a warehouse for a gangster where he helps to relocate illegal contraband, and because of his ruthlessness and dependability he begins to ascend the ladder of organized crime. Of course, the more powerful he becomes, the more "Climbers" come out of the shadows to take his place.