Presented from the point of view of Mister X, the quintessential unreliable narrator, God in 3 Persons relates the story of his involvement with a pair of conjoined twin faith healers. As the increasingly improbable story unfolds, ending with Mister X's destruction of the mysterious Holy Union, the audience never knows how much of the dubious tale is fact, fiction or the fading reminisces of an aging Lothario. Operatic in its vision and profound in its implications, God in 3 Persons examines the controversial concepts of difference and diversity, while also passionately revealing the secret soul of gender identity.

In 1960, seven outcast kids known as "The Losers' Club" fight an evil demon who poses as a child-killing clown. Thirty years later, they reunite to stop the demon once and for all when it returns to their hometown.