The special takes place during the two year before the Straw Hats reunite on Sabody. Luffy is currently in Rusukaina training to get stronger to take on the New World. However the training is interrupted when Hancock's sisters, Marigold and Sandersonia, are kidnapped by the Byrnndi World, a pirate who was locked away on Level 6 of Impel Down but escaped during Luffy's invasion to save Ace, in order to lure Hancock to him and use her as a hostage against the World Government due to her Shichibukai status. Thus Luffy and Hancock head off to confront him and save Hancock's sisters.

When Nami falls ill, the Straw Hats seek medical care for her on Drum Island. There they meet reindeer doctor Tony Tony Chopper and the Wapol Pirates.

Kitarō is a yōkai boy born in a cemetery, and aside from his mostly-decayed father, the last living member of the Ghost tribe. He is missing his left eye, but his hair usually covers the empty socket. He fights for peace between humans and yōkai, which generally involves protecting the former from the wiles of the latter.

Five years after the death of the Emperor of Marmo in the War of Heroes, Parn is now the Free Knight of Lodoss, he and his old allies now famous through the land. However, the Emperor's right-hand-man, Ashram, seeks the Scepter of Domination to re-unify Lodoss under his former leader's banner. Meanwhile, beyond his attempts at conquest lies a more sinister force beginning to set the stage for the resurrection of the goddess of death and destruction...

While enjoying the flower gardens, Sailor Moon and friends encounter an old childhood friend of Mamoru's: an alien! He's come back to give Mamoru a special flower but doesn't like Usagi and the rest of the planet's inhabitants. Sailor Moon must defend the earth from the evil Kisenian Flower he's brought back... before the evil vines and blossoms overrun the planet!