After the 1860s Wild West, a group of misfit settlers - including ex-doctor Phil Taylor, prostitute Belle, and homosexual bookseller Julian - decide they cannot live in their current situation in the west. They hire a grizzled alcoholic wagon master by the name of James Harlow to take them on a journey back to their hometowns in the East.

Anthony Cortino lives with his mother in a quiet suburb. His father is dead, and his violent criminal brother is a long way off, in the city, and if Anthony has his way, that's where he will stay. However, Johnny runs into trouble with the police in the city, and when he asks to come home, his mother agrees, despite Anthony's objections. A reign of terror begins for Anthony then, for as long as Johnny is around, Anthony is never safe, and never has been.