The Brothers García is an American sitcom that premiered in 2000 on Nickelodeon and ended in 2004. It was among the first projects of Sí TV, an effort to produce programming featuring Latino characters, however being aimed at a diverse audience. The series was billed as the first English-language sitcom to have an all Latino cast and creative team. The series aired on the programming block Nick on CBS from September 18, 2004 to September 17, 2005, where the series ended its initial run. Reruns on The N started on April 7, 2008, and ended in May 23, 2008. Similarities to the series could be made to the style of The Wonder Years and Everybody Hates Chris, with an older version of the main character narrating each episode in a witty and sarcastic manner.

Out at Pacific Coast University, five students living in the same apartment building go through personal trials.

After the 1860s Wild West, a group of misfit settlers - including ex-doctor Phil Taylor, prostitute Belle, and homosexual bookseller Julian - decide they cannot live in their current situation in the west. They hire a grizzled alcoholic wagon master by the name of James Harlow to take them on a journey back to their hometowns in the East.