First Wave is a Canadian/American science fiction television series, filmed in Vancouver, British Columbia, Canada, that aired from 1998 to 2001 on the Sci-Fi Channel. The show was created by Chris Brancato, who co-wrote an early version of the script for the seminal X-Files episode "Eve". Francis Ford Coppola was executive producer on the show. In an unusual move, the Sci-Fi Channel picked up the series on a 66-episode contract. The show was subsequently canceled once the contract expired at the end of the third season due to disappointing ratings.

A family discovers their youngest daughter has cancer. But the real struggle has yet to start.

A girl, sent by her parents to live with her two eccentric aunts, finds out on her sixteenth birthday that she is a witch.

The exploits of FBI Special Agents Fox Mulder and Dana Scully who investigate X-Files: marginalized, unsolved cases involving paranormal phenomena. Mulder believes in the existence of aliens and the paranormal while Scully, a skeptic, is assigned to make scientific analyses of Mulder's discoveries that debunk Mulder's work and thus return him to mainstream cases.