After falling victim to a humiliating prank by the high school Queen Bee, best friends and world-class geeks, Mindy and Jodi, decide to get their revenge by uniting the outcasts of the school against her and her circle of friends.

Straitlaced Princeton University admissions officer, Portia Nathan is caught off-guard when she makes a recruiting visit to an alternative high school overseen by her former college classmate, the freewheeling John Pressman. Pressman has surmised that Jeremiah, his gifted yet very unconventional student, might well be the son that Portia secretly gave up for adoption many years ago.