Don Matteo is a thoroughly ordinary Catholic priest with an extraordinary ability to read people and solve crimes. He’s a parish priest who never met an unjustly accused person he didn’t want to help.

Italy, early 80's. A political terrorist is being transferred northward from Sicily for a conjugal visit; during the journey, a police captain tries to make him cooperate.

Four waiters and a cook working at a seaside restaurant hate one another but still keep working together for lack of better opportunities.

Nanni Moretti recalls in his diary three slice of life stories characterized by a sharply ironic look: in the first one he wanders through a deserted Rome, in the second he visits a reclusive friend on an island, and in the last he has to grapple with an unknown illness.

The young priest Father Giulio returns to Rome, his hometown, after a long pilgrimage. Don Giulio hopes to live peacefully with his family and his friends, but discovers that many of them are depressed or frustrated, and some suicidal.

Michele criticizes the film industry and its inhabitants, and is particularly embattled with a Neapolitan director making a musical about the 1968 student demonstrations. At the same time, Michele has a creative block and struggles to finish his film titled "Freud’s Mother." Nanni Moretti’s self-inquiry into filmmaking, political ennui, and men’s relations with their mothers.

Mauro, a judge, is worried about his older sister Marta, who took care of him since he was a boy, and now suffers from mental illness and suicidal thoughts. She seems to recover from her depression when Mauro acquaints her with Giovanni, a brilliant actor at the edge of legality. However, Mauro becomes unconsciously jealous of their relationship.