Dr. Megan Hunt was in a class of her own, a brilliant neurosurgeon at the top of her game. But her world is turned upside down when a devastating car accident puts an end to her time in the operating room. Megan resumes her career as a medical examiner, determined to solve the puzzle of who or what killed the victims.

Allison Dubois works in the District Attorney’s office using her natural intuition about people and her ability to communicate with the dead to help to solve crimes. Her dreams often give her clues to the whereabouts of missing people.

The series follows the ventures of a Missing Persons Unit of the FBI in New York City.

Vinnie's a bookie, happily married, running his operation for 30 years out of his bar in Brooklyn. Times change, the boys up the chain want a bigger profit, so Vinnie's expendable He's assigned a hotheaded kid, Tony, the nephew of a local mobster. Vinnie's told to school the lad, use him for collections, and teach him some sense. What Vinnie doesn't know is that once Tony learns the ropes, Vinnie will be out. Tensions mount when Tony goes around Vinnie's paternalistic ways, takes a bet from an unemployed alcoholic, and demands that the loser's wife pay the vig in trade. Is there any way out for Vinnie - with or without his good name?

In cases ripped from the headlines, police investigate serious and often deadly crimes, weighing the evidence and questioning the suspects until someone is taken into custody. The district attorney's office then builds a case to convict the perpetrator by proving the person guilty beyond a reasonable doubt. Working together, these expert teams navigate all sides of the complex criminal justice system to make New York a safer place.