Two New Orleans paramedics' lives are ripped apart after encountering a series of horrific deaths linked to a designer drug with bizarre, otherworldly effects.

When best friends, Jack and Scottie, get a once in a lifetime shot at hidden loot, they take off on a cross-country adventure turned crime spree. With a whiny accidental hostage in tow, and a deranged bounty huntress and Johnny Law hot on their trail, it's going to be a race to the bullet-riddled finish.

A tropical storm floods Soggy Meadows trailer park and forces a hungry shark upriver.