Ainsley is a misanthrope who hates people but when she suddenly finds herself in isolation with no one to talk to, she realizes how much she actually misses connection. Enter Ulysses, a dead mouse in a jar. With a little bit of loneliness, a pinch of imagination, and a mouse-sized tuxedo, Ulysses becomes her training wheels in this newly discovered world of friendship.

After a comet releases a mysterious virus that begins to kill all of the women in the world, a young couple's relationship is severely tested. They hide out (from both the illness and the savages who hunt the remaining women) in their over-sterilized apartment. Ultimately the duo escapes their self-imposed quarantine to head to the wilderness.

The nicest guy in the Midwest moves his family into a tough neighborhood in Los Angeles where not everyone appreciates his extreme neighborliness. That includes their new next-door neighbor Calvin.

Dr. Beaumont Rosewood, Jr. is a brilliant private pathologist who uses wildly sophisticated technology and his drive to live life to the fullest to help a tough-as-nails detective and the Miami PD uncover clues no one else can see.