When Doctor Andrea Fanti loses 12 years of memories from a brain injury, he finds himself adjusting to a world full of strangers.

Cosimo is Italian, Nicole French. They meet in Genoa during the G8 protests and immediately fall in love. Swept off their feet by an overwhelming and uncontrollable passion, they decide never to part. After much wandering they decide to return to Genoa, where they start working for a friend of theirs who organises concerts. Things seem to be going well until a tragic accident almost sours their relationship, as a result of which they’re faced with two options that can change their future. Forever.

On July 19–21, 2001, over 200,000 people took to the streets of Genoa to protest against the ongoing G8 summit. Anti-globalization activists clashed with the police, with 23-year-old protester Carlo Giuliani shot dead after confronting a police vehicle. In the aftermath, the police organized a night raid on the Diaz high school, where around a hundred people between unarmed protesters—mostly students—and independent reporters who documented the police brutality during the protests had took shelter. What happened next was called by Amnesty International "the most serious breach of civil liberties in a democratic Western country since World War II."

Based on the case of the serial killer Donato Bilancia, who murdered 17 people between 1998 and 2000 in Genova.

While world religious leaders gather for a top secret meeting in La Spezia, the Reverend Jones, a famous television preacher and the creator of Reverend Jones's Sauce, is set on replacing them all and imposing his credo on the unsuspecting world.