Moe, Rose and Lee Baumler are members of an upper class family who find the world completely changed when they lose everything in the stock market crash of 1929. Lee, a college-age young man, who now faces no possibility of entering college, decides to go on the road to see what is happening to the rest of the country.

A quartet of murderous psychopaths break out of a mental hospital during a power blackout and lay siege to their doctor's house.