Niccolo "Mac" Vitelli is the eldest of three brothers in 1950s Queens. Mac is a construction builder, a trade he learned from his late father, and helps put his brothers on the job. When they can no longer take working for Polowski, who does shoddy work and is abusive to his staff, Mac and his brothers set up their own company. Together, Vitelli Brothers Construction builds houses with pride and care. But Mac turns out to be an overbearing workaholic, with obsessive concern about the quality of their work and incredible attention to detail. His intensity and driven ambition precludes a happy family life and begins to drive his brothers away.

After her husband loses his job, Marianne moves from Beverly Hills to a nightmare New York City. She hires ditzy psychic Reva to redecorate her apartment, and they end up being pursued by a crazed killer.

T, as most of his friends, lives in a self-constructed 'house', built on top of an old building in the city. Their one passion is 'combat'. Combat is a dance/streetfight during which the contestants try to push each other out of the arena, while not allowed to actually touch each other. When drugdealers move into the neighbourhood and kill T's best friend he embarks on a mission to eradicate the drug-presence in the neigbourhood. His friends are reluctant to help though, knowing what happened to T's friend when he crossed them.

A former Prohibition-era Jewish gangster returns to the Lower East Side of Manhattan over thirty years later, where he once again must confront the ghosts and regrets of his old life.