Giacomo, the main character, 35 years of laziness, is a man who doesn't know and doesn't want to fight. He is a introvert curmudgeon, a little bit nerd but not very social, who walks with the look downward on his device without giving to the people what they would like from him: only a little bit of attention and enthusiasm. He loses his job, he is left by his wife and coincidentally he remains closed in the women's bathroom of the art-house cinema, together with the owner's small dog.

A young Palestinian, lost in the suburbs of Rome, decides to ask the local elderly Italian man for the right way.

Friedberg/Seltzer-like spoof about popular Italian teen romance movies of the aughts (such as Tre metri sopra il cielo, Come tu mi vuoi, Ho voglia di te, Notte prima degli esami, Melissa P., etc).

Follows a criminal gang in Rome that has a near monopoly of the city's heroin trade. Besides their internal feuding, the gang has to deal with the Camorra and Sicilian Mafia that both supply its heroin, the police led by Commissioner Scialoja and the Italian secret services.