Pietro is a revered teacher, Teresa his brilliant and precocious student. Their affair is both illicit and tempestuous. After one fight, Teresa suggests that each tell the other a secret, one so shameful or shocking that were it to be made public, it would destroy that person’s life. Time passes, Pietro’s stature as a writer grows and his family settles into the comfort of a bourgeois life. But he is haunted by the possibility that Teresa may one day reappear and tear apart his world with the secret she knows.

Nic, also called "Lovely Boy", is the rising star of the roman suburbs. Tattoos and pure talent, he creates the XXG with his friend Borneo, a music duo that is headed straight to the top. Nic is then sucked into a spiral of self-destruction, which will lead him to a breaking point: he will soon have to deal with himself.

While visiting her fiancé's mother in southern Italy, a woman must fight the mysterious and malevolent curse intent on claiming her daughter.

Nurse Anna and her assistant Hans work in an old folks’ home that was once the orphanage where they were imprisoned as children, and they still seem trapped in time and space.

These are the years of the First World War and Dr. Stefano Zorzi spends his days in the Exemption Clinic in a large city of Northern Italy, where he not only takes care of soldiers who arrive from the massacre of the front, but also he fights simulation and self-harm of those who hope to be dispensed, by sending them before the Military Court. If Stefano, in fact, does his utmost to heal soldiers and send them back to fight, Dr. Giulio Farradio makes them ill, or helps them to self-injure seriously enough to be exonerated. The two doctors, who went to university together and were great friends, they not only (secretly) challenge each other on a professional level, but also on the sentimental one: they are both linked to Anna, a courageous nurse with a strong character. But when the great ‘Spanish’ fever epidemic arrived in 1918, the time for love, politics and science ends up getting confused dangerously...