Inspired by true events, college sophomore Clemence Miller is coming home to the suburbs and a bedroom in her family's basement. After dropping out of school with a newly diagnosed mental illness, she now faces the challenges of bipolar disorder, the responsibilities of adulthood, and her damaged relationships with family and friends. Clemence struggles to figure out what it means to heal without driving everyone around her… well, crazy. As if reckoning with everything and everyone she has taken for granted wasn’t enough, Clemence has to wrestle with the thought that on top of it all, she might also just have a really bad personality.

Years after a brutal attack left her in a constantly shifting reality, Kirby Mazrachi learns that a recent murder is linked to her assault. She teams with veteran reporter Dan Velazquez to understand her ever-changing present—and confront her past.

An emotional thrill ride through the day-to-day chaos of the city's most explosive hospital and the courageous team of doctors who hold it together. They will tackle unique new cases inspired by topical events, forging fiery relationships in the pulse-pounding pandemonium of the emergency room.