Following his missing fiancée Lee across the country to a bustling, neon-lit city, Buck's only plan is to search every cocktail bar, lounge and club to find her. What follows is a series of dreamlike nighttime encounters throughout increasingly strange places. Buck’s search eventually leads to the trail of a new drug that removes the barriers of death, time, and space... and the dangerous man behind it all.

An emotional thrill ride through the day-to-day chaos of the city's most explosive hospital and the courageous team of doctors who hold it together. They will tackle unique new cases inspired by topical events, forging fiery relationships in the pulse-pounding pandemonium of the emergency room.