In the near future, planet Earth is permanently altered following the sudden—and tumultuous—arrival of seven unique alien races. In the boom-town of Defiance, the newly-formed civilization of humans and aliens must learn to co-exist peacefully.

Two mutants, Rogue and Wolverine, come to a private academy for their kind whose resident superhero team, the X-Men, must oppose a terrorist organization with similar powers.

In a futuristic wasteland, a mercenary saves a woman and her son from lethal cultists.

Years ago, the Taelons came to Earth, offering friendship and technology to humanity. But there are those who believe the Taelons have more sinister motives.