After suffering a personal tragedy, and desperate for justice, Jacob Kanon, a veteran New York City police detective, embarks on the search for a twisted killer who is leaving a bloody trail of elaborate murders across Europe.

Though safely entombed in a crypt deep beneath the unforgiving desert, an ancient queen whose destiny was unjustly taken from her is awakened in our current day, bringing with her malevolence grown over millennia, and terrors that defy human comprehension.