A mafia family from New Jersey is placed in the witness relocation program to an all-Mormon community in Utah.

After the death of his wife, world-class neurosurgeon Dr. Andrew Brown leaves Manhattan and moves his family to the small town of Everwood, Colorado. There he becomes a small-town doctor and learns parenting on the fly as he raises his talented but resentful 15-year-old son Ephram and his 9-year-old daughter Delia.

When Chris falls asleep whilst supposed to be watching his little sister, Molly, she goes missing. Finding her coloring book by the river, everyone believes she drowned there and try and move on with their life. But when Chris and his best friend, Pat watch over a tape of the day she went missing some things just don't match up and Chris believes his sister was kidnapped and is still alive. Chris and Pat go on an adventure to New Mexico to prove to everyone that Molly is really still alive.