Marcus and Mike are forced to confront new threats, career changes, and midlife crises as they join the newly created elite team AMMO of the Miami police department to take down the ruthless Armando Armas, the vicious leader of a Miami drug cartel.

Columbus, Tallahassee, Wichita, and Little Rock move to the American heartland as they face off against evolved zombies, fellow survivors, and the growing pains of the snarky makeshift family.

Ever since US Diplomatic Security Service Agent Hobbs and lawless outcast Shaw first faced off, they just have traded smack talk and body blows. But when cyber-genetically enhanced anarchist Brixton's ruthless actions threaten the future of humanity, they join forces to defeat him.

Just when his time under house arrest is about to end, Scott Lang once again puts his freedom at risk to help Hope van Dyne and Dr. Hank Pym dive into the quantum realm and try to accomplish, against time and any chance of success, a very dangerous rescue mission.