New York concierge Doug Ireland wants to go into business for himself and refurbish a hotel on Roosevelt Island, N.Y., but he needs an investor. With a few weeks left before his option on the site runs out, Doug agrees to help wealthy Christian Hanover conceal his affair with salesgirl Andy Hart from his wife. Despite his own attraction to Andy, Doug tries to stay focused on getting Christian to invest $3 million in his project.

Respected lawyer, Henry Turner survives a convenience-store shooting only to find he has lost his memory, and has serious speech and mobility issues. After also losing his job—where he no longer 'fits in'—his loving wife and daughter give him all their love and support.

Alice Tate, mother of two, with a marriage of 16 years, finds herself falling for the handsome sax player, Joe. Stricken with a backache, she consults herbalist Dr. Yang, who realizes that her problems are not related to her back, but in her mind and heart. Dr. Yang's magical herbs give Alice wondrous powers, taking her out of well-established rut.

Meet the denizens of New York City: artists, prostitutes, saints, and seers. All are aspiring toward either fame or oblivion, and hoping for love and acceptance. Instead they find high rents, faithless partners, and dead-end careers.