Follows the personal and professional lives of a group of doctors at Seattle’s Grey Sloan Memorial Hospital.

Adrian Monk was once a rising star with the San Francisco Police Department, legendary for using unconventional means to solve the department's most baffling cases. But after the tragic (and still unsolved) murder of his wife Trudy, he developed an extreme case of obsessive-compulsive disorder. Now working as a private consultant, Monk continues to investigate cases in the most unconventional ways.

This is the story of four African-American "yuppies" (a banker, a doctor, a lawyer, and a "playboy") who call themselves "The Brothers". When the playboy gets engaged, the other three friends find themselves having to come to terms with their own issues of commitment and honesty...

For the past four years, San Francisco cop Jack Cates has been after an unidentified drug kingpin who calls himself the Ice Man. Jack finds a picture that proves that the Ice Man has put a price on the head of Reggie Hammond, who is scheduled to be released from prison on the next day.