The son of a notorious serial killer becomes an acclaimed criminal psychologist who uses his unique insight into how killers think to help the NYPD.

Uptight Millie Haven has always followed the rules, but when she has doubts before her big Kansas City wedding, her attitude-prone little sister Emma, the least likely of heroes, comes to the rescue. They embark on a spontaneous roadtrip to their grandmother’s farm where, with the help of Grandma Mildred, they rediscover their bond.

Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.

Chaos and rampant hormones reign when teenage counselors are left in charge during their summer-camp director's absence.