Scientists Banting, Best, Collip and Macleod at the University of Toronto as they race for a treatment to cure 13-year-old Leonard Thompson of his life-threatening diagnosis of diabetes.

Capt. Jeffery McDonald is convicted and sentenced to life in prison in 1979 for the murders of his wife and two children at their Fort Bragg home.

A mysterious criminal steals a secret state-of-the-art time machine, intent on destroying America as we know it by changing the past. Our only hope is an unexpected team: a scientist, a soldier and a history professor, who must use the machine's prototype to travel back in time to critical events. While they must make every effort not to affect the past themselves, they must also stay one step ahead of this dangerous fugitive. But can this handpicked team uncover the mystery behind it all and end his destruction before it's too late?