When a crime boss sends out his thugs to terrorize an entire city, they do whatever they want, which includes anything from petty theft to robbing the police station in broad daylight. Napoli spara! (internationally released as Weapons of Death and Naples shoots) is a "poliziottesco" film directed by Mario Caiano in 1977. It is an unofficial sequel of Napoli violenta, of which reprises the character of Gennarino (still played by Massimo Deda).

Police believe that a respectable industrialist is actually the head of drug smuggling ring in Milan.