Doctors Owen Maestro and Lola Spratt leave Children's Hospital and join a secret arm of the CDC to investigate and destroy a deadly global virus.

After seven months have passed without a culprit in her daughter's murder case, Mildred Hayes makes a bold move, painting three signs leading into her town with a controversial message directed at Bill Willoughby, the town's revered chief of police. When his second-in-command Officer Jason Dixon, an immature mother's boy with a penchant for violence, gets involved, the battle between Mildred and Ebbing's law enforcement is only exacerbated.

A slightly unhinged former Navy SEAL lands a job as a police officer in Los Angeles where he's partnered with a veteran detective trying to keep maintain a low stress level in his life.

Follows the lives and families of three adults living and growing up in the United States of America in present and past times. As their paths cross and their life stories intertwine in curious ways, we find that several of them share the same birthday - and so much more than anyone would expect.

Sonny "Sundown" Garcia is the top cocaine distributor in the United States, which has made him a very rich and powerful man. It has also made him plenty of enemies. John Doe is just such a man. A nameless man of mystery, John lives to see Sundown not just dead, but to suffer six meaningful losses before his death—his fortune, his freedom, his love, his reputation, his most valuable possession and, finally, his life. John hires six hit-men, each one assigned to inflict one of the six meaningful losses upon Sundown.

Working for the FBI's Deep Cover Operations division, Martin Odum can transform himself into a different person -- whether it's an assignment as a Serbian extremist, a corrupt Chicago police officer, a British special forces colonel, or a legendary computer hacker. But when he learns that his life, itself, may be a lie, he faces the demands of his job and a desire to solve the mystery of his identity. And given the choice between the two, Odum doesn't always make the right decision.

Follow the lives of a group of students at what is possibly the world’s worst community college in the fictional locale of Greendale, Colorado.