Once considered a teen prodigy, a recovering addict sobers up and tries to get her writing career back on track. She begins a relationship with a rising author known for his wartime memoirs.

Dr. Temperance Brennan and her colleagues at the Jeffersonian's Medico-Legal Lab assist Special Agent Seeley Booth with murder investigations when the remains are so badly decomposed, burned or destroyed that the standard identification methods are useless.

Follows the personal and professional lives of a group of doctors at Seattle’s Grey Sloan Memorial Hospital.