Inspired by the autobiographical writings of David Wojnarowicz, "Postcards From America" chronicles the abuse the artist suffered as a child at the hands of his father and his subsequent running away to New York to become a street hustler.

Henry Hackett is the workaholic editor of a New York City tabloid. He loves his job, but the long hours and low pay are leading to discontent. Also, publisher Bernie White faces financial straits, and has hatchet-man Alicia Clark—Henry's nemesis—impose unpopular cutbacks.