Life for Dee Stanton is improving at every turn. Her legal career is blossoming and her boyfriend Dominic unexpectedly proposes to her. Things were very different 11 years ago when her husband Paul was jailed for the brutal murders of four girls and Dee was hounded from her home. Dee has kept all this a secret from her 15-year-old son Jamie. Now he has discovered the truth about his father and demands to see him.

Two teens with special powers solve mysteries: Mark has the ability to read minds, while Song Li has the ability to read feelings. They are in a project run by Professor Henry Powers, who experiments with kids with special powers like the ones Mark and Song Li have. The professor's first experiment was Dr. Mary Holland, who helps Mark and Song Li solve the mysteries with Professor Powers.

Set during the 1960s in the fictional North Yorkshire village of Aidensfield, this enduringly popular series interweaves crime and medical storylines.