After accidentally killing his lead star, a has-been hollywood producer turns to an ancient herbal elixir, in the hope that it will save his career. He makes a dark deal that unleashes a band of bloodthirsty, shape-shifting, ferocious beasts on LA.

When a Native American casino controlled by the mob begins to destroy a close-knit rural town, a band of lovable low-tech misfits hatch a plan to beat them at their own game by pulling off an audacious casino heist.