Eddie Hawkins, called Hudson Hawk has just been released from ten years of prison and is planning to spend the rest of his life honestly. But then the crazy Mayflower couple blackmail him to steal some of the works of Leonardo da Vinci. If he refuses, they threaten to kill his friend Tommy.

NYPD cop John McClane's plan to reconcile with his estranged wife is thrown for a serious loop when, minutes after he arrives at her office, the entire building is overtaken by a group of terrorists. With little help from the LAPD, wisecracking McClane sets out to single-handedly rescue the hostages and bring the bad guys down.