Eddie Hawkins, called Hudson Hawk has just been released from ten years of prison and is planning to spend the rest of his life honestly. But then the crazy Mayflower couple blackmail him to steal some of the works of Leonardo da Vinci. If he refuses, they threaten to kill his friend Tommy.

Frank Leone is nearing the end of his prison term for a relatively minor crime. Just before he is paroled, however, Warden Drumgoole takes charge. Drumgoole was assigned to a hell-hole prison after his administration was publicly humiliated by Leone, and has now arrived on the scene to ensure that Leone never sees the light of day.