Surgeon Simon Thorne suffers from paranoia, obsessions and hallucinations, and loses both his wife and his job. But then he meets a couple from one of his dreams where they kill him. So he has to kill them first.

A group of attractive women get together for a weekend of bonding, hoping to relax and getaway from the anxiety of their boyfriends. The women travel out of town which leads them to picking up men of questionable integrity. The next problem is what will they tell their boyfriends when they get back home.