A homeless dying veteran, trying to find a Unicorn he believes lives in the mountains above Los Angeles, convinces a Latina immigrant to join his quest, provoking a tragic-comic chase as they are followed by the Border Patrol and her Lowrider cousins.

In the year 2517, after the arrival of humans in a new star system, follow the adventures of the renegade crew of Serenity, a "Firefly-class" spaceship. The ensemble cast portrays the nine characters who live on Serenity.