It's Christmas Eve, the city goes dark, and the few remaining tenants of The Ravenwood find themselves trapped in their building. And they are not alone.

Skeeter Bronson is a down-on-his-luck guy who's always telling bedtime stories to his niece and nephew. But his life is turned upside down when the fantastical stories he makes up for entertainment inexplicably turn into reality. Can a bewildered Skeeter manage his own unruly fantasies now that the outrageous characters and situations from his mind have morphed into actual people and events?

In the unreal world of Sacred Heart Hospital, John "J.D." Dorian learns the ways of medicine, friendship and life.