It's 1947, and hard-boiled private investigator Charlie Nickels' client is murdered and her priceless diamond stolen. The investigation forces him to do the one thing he vowed never to do again: trust a dame.

An elite team of FBI profilers analyze the country's most twisted criminal minds, anticipating their next moves before they strike again. The Behavioral Analysis Unit's most experienced agent is David Rossi, a founding member of the BAU who returns to help the team solve new cases.