Austin's hottest DJ, Jungle Julia, sets out into the night to unwind with her two friends Shanna and Arlene. Covertly tracking their moves is Stuntman Mike, a scarred rebel leering from behind the wheel of his muscle car, revving just feet away.

Grindhouse combines Robert Rodriguez's Planet Terror, a horror comedy about a group of survivors who battle zombie-like creatures, and Quentin Tarantino's Death Proof, an action thriller about a murderous stuntman who kills young women with modified vehicles. It is presented as a double feature with fictitious exploitation trailers before each segment.