In North Carolina's Appalachian Mountains, eighteen-year-old Jacob McNeely is torn between appeasing his meth-dealing kingpin father and leaving the mountains forever with the girl he loves.

Growing up in post-World War II era Arizona, young Sammy Fabelman aspires to become a filmmaker as he reaches adolescence, but soon discovers a shattering family secret and explores how the power of films can help him see the truth.

When Christy discovers her 10-year-old daughter Anna has a rare, incurable disease, she becomes a ferocious advocate for her daughter’s healing as she searches for a solution. After Anna has a freak accident and falls three stories, a miracle unfolds in the wake of her dramatic rescue that leaves medical specialists mystified, her family restored and their community inspired.