Charlie and Dan have been best friends and business partners for thirty years; their Manhattan public relations firm is on the verge of a huge business deal with a Japanese company. With two weeks to sew up the contract, Dan gets a surprise: a woman he married on a drunken impulse nearly nine years before (annulled the next day) shows up to tell him he's the father of her twins, now seven, and she'll be in jail for 14 days for a political protest. Dan volunteers to keep the tykes, although he's up tight and clueless. With Charlie's help is there any way they can be dad and uncle, meet the kids' expectations, and still land the account?

In this sequel to the Off-Broadway musical hit, the Little Sisters of Hoboken put together another musical revue, to thank all the people who saw the first show and helped them solve their little "monetary" problem.

An unfortunate convent cooking accident causes most of the order of the Little Sisters of Hoboken to die of botulism. Before all of the deceased sisters can be buried, Reverend Mother Superior (Rue McClanahan) buys a camcorder and VCR for the convent - resulting in not having enough money to bury the four remaining sisters (which, by the way, are temporarily being stored in the freezer). In order to raise money to bury the four dead sisters, the Little Sisters of Hoboken (well, what's left of them) put on a riotous revue packed with hilarious, show-stopping song and dance numbers.