A hotel room shootout between two assassins kicks off a long night where bodies fall like dominoes, as we follow a chain of crooked cops, gangsters, hitmen, a femme Fatale and an ex-mercenary through a relay of murder, betrayal, revenge and redemption.

The film chronicles the rise and fall of the world's most feared drug lord Pablo Escobar and his volatile love affair with Colombia's most famous journalist Virginia Vallejo throughout a reign of terror that tore a country apart.