The film chronicles the rise and fall of the world's most feared drug lord Pablo Escobar and his volatile love affair with Colombia's most famous journalist Virginia Vallejo throughout a reign of terror that tore a country apart.

Terror reaches new heights when a gang of terrorists steals radioactive material from a nuclear power plant. Although they manage to escape by plane, the pilot is critically injured and they are forced to make an emergency landing. Presenting themselves as a commercial flight, they are granted access to a small private airport. Once on earth, the terrorists kidnap the owner, his daughter and the rest of the staff, forcing them to repair the plane and pilot it to finish the mission.