Salmon Run focuses on the impact that farm raised Atlantic salmon has on a small fishing community in Naknek, Alaska, a town dependent on the annual wild salmon run.

On the afternoon of July 1, 1981, Los Angeles police responded to a distress call on Wonderland Avenue and discovered a grisly quadruple homicide. The police investigation that followed uncovered two versions of the events leading up to the brutal murders - both involving legendary porn actor John Holmes.