Hoping to save his sick mother, a boy named Gunner and his friend Jo venture into the remote Wild Horse forest to search for a mythical figure who possesses the secret to immortality. When they go missing, Gunner's father Amos must immerse himself in his son's world to find them.

Foster siblings Vincent and Krystal have been estranged for many years. When they are forced to reunite, their polar opposite paths in life lead to an explosive outcome where each is made to come to terms with their own faults. Vincent is a pastor of a small church struggling with religious doubts and a burgeoning desire for another male pastor. Krystal, on the other hand, has devoted her life to full on exploration and hedonism through the arts yet struggles with the labels placed on her as a result. As each other's closest confidant as well as biggest critic, Vincent and Krystal attract and repel like magnets. When the siblings reunite, everything comes to a head, both within their relationship and within each of their individual lives.

After Portland homicide detective Nick Burkhardt discovers he's descended from an elite line of criminal profilers known as "Grimms," he increasingly finds his responsibilities as a detective at odds with his new responsibilities as a Grimm.