A family, trying to pull themselves together after losing their infant son, moves into a new home, where, almost immediately, the mother begins experiencing paranormal phenomena. She finds it playful at first, but as it grows increasingly malevolent, she is unable to convince her husband of it, and she must contend with it to protect her family from its influence.

Since her divorce nurse Abbey lives alone with her 6 years old son Willie. Her ex-husband Ted may have Willie every second weekend. But when Ted marries Clare, who has two children herself, he wants to see Willie more and more often.

ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.