When a thirty-something couple set aside the home furnishings catalogue and decide to rekindle their relationship, they return to their old neighborhood and end up squatting illegally in their twenty-something lives.

A young boy fighting cancer writes letters to God, touching lives in his neighborhood and inspiring hope among everyone he comes in contact. An unsuspecting substitute postman, with a troubled life of his own, becomes entangled in the boy's journey and his family by reading the letters. They inspire him to seek a better life for himself and his own son he's lost through his alcohol addiction.

An elite team of FBI profilers analyze the country's most twisted criminal minds, anticipating their next moves before they strike again. The Behavioral Analysis Unit's most experienced agent is David Rossi, a founding member of the BAU who returns to help the team solve new cases.