Mad scientist Prospero runs away with his blind daughter Miranda to Tromaville, hiding from evil pharmaceutical execs, including his own sister Antoinette who ruined his career after he found the cure against opioid addiction. With the help of a handicapped crack-whore, he releases a massive amount of laxative to whales, while his enemies are on a cruise ship to North Korea. A humongous shitstorm washes the boat away and brings them to Tromaville, where Prospero can now fully realize his ultimate vengeance.

Robert Neville is a scientist who was unable to stop the spread of the terrible virus that was incurable and man-made. Immune, Neville is now the last human survivor in what is left of New York City and perhaps the world. For three years, Neville has faithfully sent out daily radio messages, desperate to find any other survivors who might be out there. But he is not alone.

When New York architect Matt Saunders dumps his new girlfriend Jenny Johnson - a smart, sexy and reluctant superhero known as G-Girl - she uses her powers to make his life a living hell!

A documentary about the making of provocateur Lloyd Kaufman's cinematic opus, #Shakespeare's Shitstorm.