Doogie Howser is a doctor. He is also a 16-year-old genius who graduated college at age 10 and finished medical school at age 14. But he is still a teenager, with normal teenage friends and problems. But unlike a normal teenager, he is just learning to drive while also consulting on serious medical cases like heart transplants.

A probationary angel is sent back to Earth to team up with an ex-cop and help people.

Moments before being surprised at an anniversary garden party thrown by her husband and their family and friends, Carol Sherwood shocks him by saying she wants a divorce and during the course of the party, she has three separate fantasies with three different men in attendance of being married to them. The first is with egotistical real estate magnate Craig Wyler. The second is with milquetoast English professor David Koenig. The third is with her best friend Elaine's husband Phil.

Divorced for two years, Nancy Caruthers, asks her new lover, Paul Adams, a medical student, to move in. She has custody of her two daughters, but this new living arrangement prompts her ex-husband, Richard to sue for custody, based on moral grounds. He does not really want the girls to live with him, but his strict religious background will not allow him to stand by and let them be raised in an atmosphere of 'sin.'